Hydrogen Deuterium Exchange (HDX)
Mass Spectrometry (MS)
Instrumentation
We use mass spectrometers from the Waters Corporation. In collaboration with Waters, we developed an instrumental system for HDX MS. Our laboratory is a Waters Corporation Center of Innovation.
The Waters HDX MS system is summarized in the following video:
Current Mass Spectrometers
SELECT SERIES Cyclic IMS
Electrospray quadrupole, cyclic ion-mobility MS/MS, high-resolution time-of-flight
DETAILS
Synapt XS
Electrospray quadrupole, stepwave XS, ion-mobility MS/MS, extended TOF
DETAILS
Synapt G2-Si #1
Electrospray quadrupole, ion-mobility MS/MS, high-resolution time-of-flight
DETAILS
Synapt G2-Si #2
Electrospray quadrupole, ion-mobility MS/MS, high-resolution time-of-flight
DETAILS
Xevo G2 QTof
Electrospray, MS/MS, Time-of-Flight
DETAILS
Chromatography Instrumentation and Robotics
Multiple UPLC systems
UPLCs for HDX MS
based on this publication
LEAP H/D-X PAL
Custom HDX sample prep robot
